BDBM768893 (S)-1-(4-(2-(2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)phenyl)cyclopropan-1-amine::US12410160, Example 295

SMILES C[C@H]1CCN1c1nc2c(c(-c3ccc(C4(N)CC4)cc3)n1)CCC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 768893   

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM768893((S)-1-(4-(2-(2-methylazetidin-1-yl)-6,7-dihydro-5H...)
Affinity DataIC50: 1.40nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandPNGBDBM768893((S)-1-(4-(2-(2-methylazetidin-1-yl)-6,7-dihydro-5H...)
Affinity DataIC50: 2.60nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent