BDBM768910 (S)-1-(4-(2-(2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)phenyl)cyclobutan-1-amine::US12410160, Example 312

SMILES C[C@H]1CCN1c1nc2c(c(-c3ccc(C4(N)CCC4)cc3)n1)CCC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 768910   

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM768910((S)-1-(4-(2-(2-methylazetidin-1-yl)-6,7-dihydro-5H...)
Affinity DataIC50: 0.900nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandPNGBDBM768910((S)-1-(4-(2-(2-methylazetidin-1-yl)-6,7-dihydro-5H...)
Affinity DataIC50: 1.20nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent