BDBM769075 N-(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-4-methoxy-2,3-dihydrobenzofuran-3-yl)methanesulfonamide::US12410160, Example 477

SMILES COc1cc(-c2nc(N3C[C@@H](O)[C@@H]3C)nc3c2CCC3(F)F)cc2c1C(NS(C)(=O)=O)CO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 769075   

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769075(N-(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylaz...)
Affinity DataIC50: 0.400nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent