BDBM769161 (S)-(5-(2-((S)-3,3-difluoro-2-methylazetidin-1-yl)-7,7-difluoro-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-2-methoxyphenyl)(imino)(methyl)-lambda6-sulfanone::US12410160, Example 563

SMILES COc1ccc(-c2nc(N3CC(F)(F)[C@@H]3C)nc3c2CCC3(F)F)cc1[S@@](C)(=N)=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769161   

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769161((S)-(5-(2-((S)-3,3-difluoro-2-methylazetidin-1-yl)...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769161((S)-(5-(2-((S)-3,3-difluoro-2-methylazetidin-1-yl)...)
Affinity DataIC50: 1.70nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent