BDBM769229 N-((S)-5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3,3-dimethyl-2,3-dihydro-1H-inden-1-yl)methanesulfonamide::US12410160, Example 632

SMILES C[C@H]1[C@H](O)CN1c1nc(-c2ccc3c(c2)C(C)(C)C[C@@H]3NS(C)(=O)=O)c2c(n1)C(F)(F)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 769229   

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769229(N-((S)-5-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-meth...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent