BDBM769272 N-[6-[7,7-difluoro-2-[(2S,3R)-3-fluoro-2-methyl-azetidin-1-yl]-5,6-dihydrocyclopenta[d]pyrimidin-4-yl]-1,1-dioxo-2,3-dihydrobenzothiophen-3-yl]methanesulfonamide::US12410160, Example 675

SMILES C[C@H]1[C@H](F)CN1c1nc(-c2ccc3c(c2)S(=O)(=O)CC3NS(C)(=O)=O)c2c(n1)C(F)(F)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 769272   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM769272(N-[6-[7,7-difluoro-2-[(2S,3R)-3-fluoro-2-methyl-az...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent