BDBM769273 (5S)-5''-[7,7-difluoro-2-[(2R)-2-(fluoromethyl)azetidin-1-yl]-5,6-dihydrocyclopenta[d]pyrimidin-4-yl]-3-methyl-spiro[imidazolidine-5,1''-indane]-2,4-dione::US12410160, Example 676

SMILES CN1C(=O)N[C@]2(CCc3cc(-c4nc(N5CC[C@@H]5CF)nc5c4CCC5(F)F)ccc32)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 769273   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM769273((5S)-5'-[7,7-difluoro-2-[(2R)-2-(fluoromethyl)azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent