BDBM769278 N-[(3R)-6-[2-[(2S)-3,3-difluoro-2-methyl-azetidin-1-yl]-7,7-difluoro-5,6-dihydrocyclopenta[d]pyrimidin-4-yl]-1,1-dioxo-2,3-dihydrobenzothiophen-3-yl]methanesulfonamide::US12410160, Example 681

SMILES C[C@@H]1N(c2nc(-c3ccc4c(c3)S(=O)(=O)C[C@@H]4NS(C)(=O)=O)c3c(n2)C(F)(F)CC3)CC1(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 769278   

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769278(N-[(3R)-6-[2-[(2S)-3,3-difluoro-2-methyl-azetidin-...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent