BDBM769287 6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-1''-isopropyl-2H-spiro[benzofuran-3,4''-imidazolidine]-2'',5''-dione::US12410160, Example 690

SMILES CC(C)N1C(=O)NC2(COc3cc(-c4nc(N5C[C@@H](O)[C@@H]5C)nc5c4CCC5(F)F)ccc32)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769287   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM769287(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.300nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM769287(6-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 45.4nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent