BDBM769290 6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azetidin-1-yl]-5,6-dihydrocyclopenta[d]pyrimidin-4-yl]-3''-propyl-spiro[2H-benzofuran-3,5''-imidazolidine]-2'',4''-dione::US12410160, Example 693

SMILES CCCN1C(=O)NC2(COc3cc(-c4nc(N5C[C@@H](O)[C@@H]5C)nc5c4CCC5(F)F)ccc32)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769290   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM769290(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM769290(6-[7,7-difluoro-2-[(2S,3R)-3-hydroxy-2-methyl-azet...)
Affinity DataIC50: 47.2nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent