BDBM769322 8-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-1-imino-2,3,4,5-tetrahydro-benzo[f][1,4]thiazepine 1-oxide::US12410160, Example 725

SMILES C[C@H]1[C@H](O)CN1c1nc(-c2ccc3c(c2)S(=N)(=O)CCNC3)c2c(n1)C(F)(F)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769322   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM769322(8-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 0.900nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM769322(8-(7,7-difluoro-2-((2S,3R)-3-hydroxy-2-methylazeti...)
Affinity DataIC50: 2.20nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent