BDBM769394 3-amino-3-(4-(7,7-difluoro-2-((2S,3R)-3-fluoro-2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)phenyl)-1-imino-1lambda6-thietane 1-oxide::US12410160, Example 797

SMILES C[C@H]1[C@H](F)CN1c1nc(-c2ccc(C3(N)CS(=N)(=O)C3)cc2)c2c(n1)C(F)(F)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769394   

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769394(3-amino-3-(4-(7,7-difluoro-2-((2S,3R)-3-fluoro-2-m...)
Affinity DataIC50: 0.200nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769394(3-amino-3-(4-(7,7-difluoro-2-((2S,3R)-3-fluoro-2-m...)
Affinity DataIC50: 7.30nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent