BDBM769400 3-amino-3-(4-(7,7-difluoro-2-((R)-2-(trifluoromethyl)azetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)phenyl)propanenitrile::US12410160, Example 803

SMILES N#CCC(N)c1ccc(-c2nc(N3CC[C@@H]3C(F)(F)F)nc3c2CCC3(F)F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769400   

TargetKetohexokinase(Human)TBA
LigandPNGBDBM769400(3-amino-3-(4-(7,7-difluoro-2-((R)-2-(trifluorometh...)
Affinity DataIC50: 0.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM769400(3-amino-3-(4-(7,7-difluoro-2-((R)-2-(trifluorometh...)
Affinity DataIC50: 0.800nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent