BDBM769429 (2S,3R)-1-[4-[3-(difluoromethylsulfonimidoyl)-4-methoxy-phenyl]-7,7-difluoro-5,6-dihydrocyclopenta[d]pyrimidin-2-yl]-2-methyl-azetidin-3-ol::US12410160, Example 832

SMILES COc1ccc(-c2nc(N3C[C@@H](O)[C@@H]3C)nc3c2CCC3(F)F)cc1S(=N)(=O)C(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769429   

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769429((2S,3R)-1-[4-[3-(difluoromethylsulfonimidoyl)-4-me...)
Affinity DataIC50: 2.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769429((2S,3R)-1-[4-[3-(difluoromethylsulfonimidoyl)-4-me...)
Affinity DataIC50: 5.70nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent