BDBM769441 ((1,3-dioxan-5-yl)methyl)(imino)(2-methoxy-5-(2-((S)-2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)phenyl)-lambda6-sulfanone::US12410160, Example 844

SMILES COc1ccc(-c2nc(N3CC[C@@H]3C)nc3c2CCC3)cc1S(=N)(=O)CC1COCOC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769441   

TargetIsoform A of Ketohexokinase (Peripheral)(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769441(((1,3-dioxan-5-yl)methyl)(imino)(2-methoxy-5-(2-((...)
Affinity DataIC50: 2.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetKetohexokinase(Human)
Gilead Sciences

US Patent
LigandPNGBDBM769441(((1,3-dioxan-5-yl)methyl)(imino)(2-methoxy-5-(2-((...)
Affinity DataIC50: 8.5nMAssay Description:Compounds were tested for KHK enzyme inhibition in a high-throughput 384-well assay format using the ADP-Glo assay (Promega) in buffer consisting of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent