BDBM769496 (3R)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-pentaazapentacyclo[13.5.2.18,11.04,9.018,22]tricosa-1(21),4,6,8,15::US12410191, Example 5

SMILES C[C@H]1Nc2ccn3ncc(c3n2)C(=O)NCC2(C)Cc3cc(F)cc1c3O2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 769496   

TargetBDNF/NT-3 growth factors receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769496((3R)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-p...)
Affinity DataIC50: 0.760nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769496((3R)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-p...)
Affinity DataIC50: 0.920nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769496((3R)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-p...)
Affinity DataIC50: 2.63nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769496((3R)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-p...)
Affinity DataIC50: 4.31nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769496((3R)-6-fluoro-3,11-dimethyl-10-oxa-2,13,17,18,21-p...)
Affinity DataIC50: 14.5nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent