BDBM769497 (3R)-6-fluoro-3-methyl-10-oxa-2,14,18,19,22-pentaazapentacyclo[14.5.2.18,11.04,9.019,23]tetracosa-1(22),4,6,8,11(24),16::US12410191, Example 6

SMILES C[C@H]1Nc2ccn3ncc(c3n2)C(=O)NCCc2cc3cc(F)cc1c3o2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 769497   

TargetBDNF/NT-3 growth factors receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769497((3R)-6-fluoro-3-methyl-10-oxa-2,14,18,19,22-pentaa...)
Affinity DataIC50: 0.340nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769497((3R)-6-fluoro-3-methyl-10-oxa-2,14,18,19,22-pentaa...)
Affinity DataIC50: 1.05nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769497((3R)-6-fluoro-3-methyl-10-oxa-2,14,18,19,22-pentaa...)
Affinity DataIC50: 11.3nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent