BDBM769499 (2R,14R)-19-fluoro-2-methyl-16,22-dioxa-3,5,7,8,12-pentaazapentacyclo[12.6.2.24,7.06,10.017,21]tetracosa-1(20),4,6(10),8,17::US12410191, Example 7

SMILES C[C@H]1Nc2ccn3ncc(c3n2)C(=O)NC[C@@H]2COc3cc(F)cc1c3O2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 769499   

TargetBDNF/NT-3 growth factors receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769499((2R,14R)-19-fluoro-2-methyl-16,22-dioxa-3,5,7,8,12...)
Affinity DataIC50: 0.320nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769499((2R,14R)-19-fluoro-2-methyl-16,22-dioxa-3,5,7,8,12...)
Affinity DataIC50: 2.05nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769499((2R,14R)-19-fluoro-2-methyl-16,22-dioxa-3,5,7,8,12...)
Affinity DataIC50: 2.65nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G667C](Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769499((2R,14R)-19-fluoro-2-methyl-16,22-dioxa-3,5,7,8,12...)
Affinity DataIC50: 21.1nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetNT-3 growth factor receptor [G623R](Homo sapiens (Human))
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769499((2R,14R)-19-fluoro-2-methyl-16,22-dioxa-3,5,7,8,12...)
Affinity DataIC50: 25.3nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent