BDBM769501 (3R,11S)-5,6-difluoro-3,11-dimethyl-10-oxa-2,13,17, 18,21-pentaazapentacyclo[13.5.2.18,11.04,9.018,22] tricosa-1(21),4,6,8,15(22),16,19-heptaen-14-one::US12410191, Example 11

SMILES C[C@H]1Nc2ccn3ncc(c3n2)C(=O)NC[C@]2(C)Cc3cc(F)c(F)c1c3O2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769501   

TargetNT-3 growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769501((3R,11S)-5,6-difluoro-3,11-dimethyl-10-oxa-2,13,17...)
Affinity DataIC50: 0.630nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769501((3R,11S)-5,6-difluoro-3,11-dimethyl-10-oxa-2,13,17...)
Affinity DataIC50: 4.5nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent