BDBM769504 (3R)-6-fluoro-11-(hydroxymethyl)-3-methyl-10-oxa- 2,13,17,18,21-pentaazapentacyclo[13.5.2.18,11.04,9. 018,22]tricosa-1(21),4,6,8,15(22),16,19-heptaen-14- one::US12410191, Example 19

SMILES C[C@H]1Nc2ccn3ncc(c3n2)C(=O)NCC2(CO)Cc3cc(F)cc1c3O2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 769504   

TargetBDNF/NT-3 growth factors receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769504((3R)-6-fluoro-11-(hydroxymethyl)-3-methyl-10-oxa- ...)
Affinity DataIC50: 0.25nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769504((3R)-6-fluoro-11-(hydroxymethyl)-3-methyl-10-oxa- ...)
Affinity DataIC50: 1.16nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769504((3R)-6-fluoro-11-(hydroxymethyl)-3-methyl-10-oxa- ...)
Affinity DataIC50: 3.40nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769504((3R)-6-fluoro-11-(hydroxymethyl)-3-methyl-10-oxa- ...)
Affinity DataIC50: 19.3nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent