BDBM769508 (2R,14R)-19-fluoro-2,14-dimethyl-16,22-dioxa-3,5, 7,8,12-pentaazapentacyclo[12.6.2.24,7.06,10.017,21] tetracosa-1(20),4,6(10),8,17(21),18,23-heptaen-11-one::US12410191, Example 23

SMILES C[C@H]1Nc2ccn3ncc(c3n2)C(=O)NC[C@]2(C)COc3cc(F)cc1c3O2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 769508   

TargetHigh affinity nerve growth factor receptor(Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769508((2R,14R)-19-fluoro-2,14-dimethyl-16,22-dioxa-3,5, ...)
Affinity DataIC50: 4.83nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Zhejiang Hisun Pharmaceutical

US Patent
LigandPNGBDBM769508((2R,14R)-19-fluoro-2,14-dimethyl-16,22-dioxa-3,5, ...)
Affinity DataIC50: 15.3nMAssay Description:Table 1: The experimental methods were operated according to the steps in the kit instruction, and were briefly described as follows: a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent