BDBM77005 3-(4-(4-(2-morpholin-4-yl-ethoxy)-benzyloxy)-1-oxoisoindolin-2-yl)-piperidine-2,6-dione::US9694015, 6.6

SMILES O=C1N(Cc2c1cccc2OCc1ccc(OCCN2CCOCC2)cc1)C1CCC(=O)NC1=O

InChI Key InChIKey=ADGAJEWJLBZHMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77005   

TargetTumor necrosis factor(Human)
Celgene

US Patent
LigandPNGBDBM77005(3-(4-(4-(2-morpholin-4-yl-ethoxy)-benzyloxy)-1-oxo...)
Affinity DataIC50: 0.960nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a 20° C. freezer prio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2018
Entry Details
US Patent