BDBM770067 (R)-N-(4- (hexahydropyrrolo[1,2- a]pyrazin-2(1H)-yl)phenyl)-4- ((8-methyl-2,3-dihydro-1H- pyrido[2,3-b][1,4]oxazin-7- yl)amino)-2-oxo-1,2- dihydropyridine-3- carboxamide::US20250282794, Example 329

SMILES Cc1c(Nc2cc[nH]c(=O)c2C(=O)Nc2ccc(N3CCN4CCC[C@@H]4C3)cc2)cnc2c1NCCO2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 770067   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Curadev Pharma

US Patent
LigandPNGBDBM770067((R)-N-(4- (hexahydropyrrolo[1,2- a]pyrazin-2(1H)-y...)
Affinity DataIC50: 10nMAssay Description:Compound inhibitory potency was measured in an HPK-1 kinase inhibition assay. Briefly, recombinant full length HPK-1 enzyme (6.8 nM) was incubated wi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent