BDBM77008 3-{4-[4-(2-morpholin-4-yl-ethyl)-benzyloxy]-1-oxo-1,3-dihydro-isoindol-2-yl}-piperidine-2,6-dione::US9694015, 6.7

SMILES O=C1N(Cc2c1cccc2OCc1ccc(CCN2CCOCC2)cc1)C1CCC(=O)NC1=O

InChI Key InChIKey=NAZVYHJDSYBQMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77008   

TargetTumor necrosis factor(Homo sapiens (Human))
Celgene

US Patent
LigandPNGBDBM77008(3-{4-[4-(2-morpholin-4-yl-ethyl)-benzyloxy]-1-oxo-...)
Affinity DataIC50:  0.790nMT: 2°CAssay Description:The Fix buffer I was warmed up to 37° C. in an incubator or water bath prior to use. The Perm Buffer III was chilled in a ⿿20° C. freezer p...More data for this Ligand-Target Pair
In DepthDetails US Patent