BDBM770165 US20250282798, Compound 12

SMILES O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc4c(n3)OC[C@H]3COCC[C@@H]43)c21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770165   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM770165(US20250282798, Compound 12)
Affinity DataIC50: 0.900nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Medshine Discovery

US Patent
LigandPNGBDBM770165(US20250282798, Compound 12)
Affinity DataIC50: 173nMAssay Description:Table 4: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound on human ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent