BDBM770173 US20250282798, Compound 21

SMILES O=C1NCc2c(-c3cnc4cc(F)ccn34)ccc(Nc3ccc4c(n3)CNC(=O)[C@H]3COC[C@@H]43)c21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 770173   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Medshine Discovery

US Patent
LigandPNGBDBM770173(US20250282798, Compound 21)
Affinity DataIC50: 0.0600nMAssay Description:Table 2: Method 2: The IC50 value was assayed by the kinase activity assay using ADP-Glo method to evaluate the inhibitory ability of a test compound...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/22/2025
Entry Details
US Patent