BDBM770313 (R)-N-((3S,4S)-4-(3,5-difluorophenyl)-1-(7-fluoroimidazo[1,5-a]pyridine-8-carbonyl)piperidin-3-yl)-3-methyl-2-(2,2,2-trifluoroacetamido)butanamide::WO2024107778, Compound 122

SMILES CC(C)[C@@H](NC(=O)C(F)(F)F)C(=O)N[C@@H]1CN(C(=O)c2c(F)ccn3cncc23)CC[C@H]1c1cc(F)cc(F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 770313   

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandPNGBDBM770313((R)-N-((3S,4S)-4-(3,5-difluorophenyl)-1-(7-fluoroi...)
Affinity DataIC50: 10.5nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetReplicase polyprotein 1ab(2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandPNGBDBM770313((R)-N-((3S,4S)-4-(3,5-difluorophenyl)-1-(7-fluoroi...)
Affinity DataIC50: 11nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetReplicase polyprotein 1ab [L3313F](2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandPNGBDBM770313((R)-N-((3S,4S)-4-(3,5-difluorophenyl)-1-(7-fluoroi...)
Affinity DataIC50: 14nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetReplicase polyprotein 1ab [L3430F]](2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandPNGBDBM770313((R)-N-((3S,4S)-4-(3,5-difluorophenyl)-1-(7-fluoroi...)
Affinity DataIC50: 206nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetReplicase polyprotein 1ab [E3429A](2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandPNGBDBM770313((R)-N-((3S,4S)-4-(3,5-difluorophenyl)-1-(7-fluoroi...)
Affinity DataIC50: 222nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778

TargetReplicase polyprotein 1ab [L3313F,E3429A,L3430F](2019-nCoV)
Takeda Pharmaceutical

WIPO
LigandPNGBDBM770313((R)-N-((3S,4S)-4-(3,5-difluorophenyl)-1-(7-fluoroi...)
Affinity DataIC50: 1.49E+3nMAssay Description: Compounds are 3 fold serially diluted for 10 doses and added to an assay plate (384w format) using ECHO, in duplicate wells. The test concentration ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2024107778