BDBM770625 2-(3-((4-(2-(2-aminopyridin-3-yl)-6-(4-benzamidophenyl)-3H-imidazo[4,5-b]pyridin-3-yl)benzyl)carbamoyl)phenyl)acetic acid::WO2025059562, Compound 86

SMILES Nc1ncccc1-c1nc2cc(-c3ccc(NC(=O)c4ccccc4)cc3)cnc2n1-c1ccc(CNC(=O)c2cccc(CC(=O)O)c2)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770625   

TargetRAC-alpha serine/threonine-protein kinase [E17K](Human)
C/O Atavistik Bio

WIPO
LigandPNGBDBM770625(2-(3-((4-(2-(2-aminopyridin-3-yl)-6-(4-benzamidoph...)
Affinity DataIC50: 50nMAssay Description:Purified human recombinant kinase full-length AKT1 E17K was expressed in insect cells and activated in vitro by PDPK1. UlightTM-CREBtide (PerkinElmer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025059562

TargetRAC-alpha serine/threonine-protein kinase(Human)
C/O Atavistik Bio

WIPO
LigandPNGBDBM770625(2-(3-((4-(2-(2-aminopyridin-3-yl)-6-(4-benzamidoph...)
Affinity DataIC50: 500nMAssay Description:Purified human recombinant kinase full-length AKT1 E17K was expressed in insect cells and activated in vitro by PDPK1. UlightTM-CREBtide (PerkinElmer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025059562