BDBM770689 4-(4-(2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[4,5-b]pyridin-3-yl)benzamido)-3-fluorobenzoic acid::WO2025059562, Compound 180

SMILES Nc1ncccc1-c1nc2ccc(-c3ccccc3)nc2n1-c1ccc(C(=O)Nc2ccc(C(=O)O)cc2F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770689   

TargetRAC-alpha serine/threonine-protein kinase [E17K](Human)
C/O Atavistik Bio

WIPO
LigandPNGBDBM770689(4-(4-(2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[...)
Affinity DataIC50: 50nMAssay Description:Purified human recombinant kinase full-length AKT1 E17K was expressed in insect cells and activated in vitro by PDPK1. UlightTM-CREBtide (PerkinElmer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025059562

TargetRAC-alpha serine/threonine-protein kinase(Human)
C/O Atavistik Bio

WIPO
LigandPNGBDBM770689(4-(4-(2-(2-aminopyridin-3-yl)-5-phenyl-3H-imidazo[...)
Affinity DataIC50: 500nMAssay Description:Purified human recombinant kinase full-length AKT1 E17K was expressed in insect cells and activated in vitro by PDPK1. UlightTM-CREBtide (PerkinElmer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025059562