BDBM770714 (S)-2-((S)-4,4-difluoro-3-(6-(hydroxymethyl)-5-oxo-4,5-dihydropyrazin-2-yl)piperidin-1-yl)-N-(6,7-dihydro-5H-indeno[5,6-d]thiazol-2-yl)propanamide::WO2025064535, Compound 20

SMILES FC1([C@@H](CN(CC1)[C@H](C(=O)NC=1SC2=C(N1)C=C1CCCC1=C2)C)C=2N=C(C(NC2)=O)CO)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 770714   

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770714((S)-2-((S)-4,4-difluoro-3-(6-(hydroxymethyl)-5-oxo...)
Affinity DataIC50: 58nMAssay Description:FlpIn TRex-MRGPRX2-HEK293 cells (herein TRex-MRPGRX2-HEK) stably transfected to express human MRGPRX2 were maintained at 37oC with 5% CO2 and grown i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535