BDBM770716 (S)-2-((S)-3-(5-((R)-1-amino-2,2-difluoroethyl)-6-oxo-1,6-dihydropyridin-3-yl)-4,4-difluoropiperidin-1-yl)-N-(2,2-difluoro-[1,3]dioxolo[4'',5'':4,5]benzo[1,2-d]thiazol-6-yl)propanamide::WO2025064535, Compound 22

SMILES N[C@@H](C(F)F)C1=CC(=CNC1=O)[C@H]1CN(CCC1(F)F)[C@H](C(=O)NC=1SC2=C(N1)C=C1C(=C2)OC(O1)(F)F)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 770716   

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770716((S)-2-((S)-3-(5-((R)-1-amino-2,2-difluoroethyl)-6-...)
Affinity DataIC50: 17nMAssay Description:FlpIn TRex-MRGPRX2-HEK293 cells (herein TRex-MRPGRX2-HEK) stably transfected to express human MRGPRX2 were maintained at 37oC with 5% CO2 and grown i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535