BDBM770739 (S)-N-(2,2-difluoro-[1,3]dioxolo[4'',5'':4,5]benzo[1,2-d]thiazol-6-yl)-2-((R)-3-(5-((S)-1,2-dihydroxyethyl)-6-oxo-1,6-dihydropyridin-3-yl)-4,4-difluoropiperidin-1-yl)propanamide::WO2025064535, Compound 45

SMILES FC1(OC=2C(=CC3=C(N=C(S3)NC([C@H](C)N3C[C@H](C(CC3)(F)F)C3=CNC(C(=C3)[C@@H](CO)O)=O)=O)C2)O1)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 770739   

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770739((S)-N-(2,2-difluoro-[1,3]dioxolo[4',5':4,5]benzo[1...)
Affinity DataIC50: 22nMAssay Description:FlpIn TRex-MRGPRX2-HEK293 cells (herein TRex-MRPGRX2-HEK) stably transfected to express human MRGPRX2 were maintained at 37oC with 5% CO2 and grown i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535