BDBM770760 4-((S)-1-((R)-1-([1,3]dioxolo[4'',5'':4,5]benzo[1,2-d]thiazol-6-ylamino)-1-oxopropan-2-yl)-4,4-difluoropiperidin-3-yl)pyridine 1-oxide::WO2025064535, Compound 81

SMILES O1COC2=CC3=C(N=C(S3)NC([C@@H](C)N3C[C@@H](C(CC3)(F)F)C3=CC=[N+](C=C3)[O-])=O)C=C21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770760   

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770760(4-((S)-1-((R)-1-([1,3]dioxolo[4',5':4,5]benzo[1,2-...)
Affinity DataIC50: 3.70nMAssay Description:FlpIn TRex-MRGPRX2-HEK293 cells (herein TRex-MRPGRX2-HEK) stably transfected to express human MRGPRX2 were maintained at 37oC with 5% CO2 and grown i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770760(4-((S)-1-((R)-1-([1,3]dioxolo[4',5':4,5]benzo[1,2-...)
Affinity DataIC50: 12nMAssay Description:LAD-2 cells were maintained at 37oC with 5% CO2 and grown in complete StemPro-34 media supplemented with 1% L-Glutamate, 1% penicillin/streptomycin, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535