BDBM770776 4-((R)-1-((S)-1-((2,2-difluoro-[1,3]dioxolo[4'',5'':4,5]benzo[1,2-d]thiazol-6-yl)amino)-1-oxopropan-2-yl)-4,4-difluoropiperidin-3-yl)-2-(hydroxymethyl)pyridine 1-oxide::WO2025064535, Compound 97

SMILES FC1(OC=2C(=CC3=C(N=C(S3)NC([C@H](C)N3C[C@H](C(CC3)(F)F)C3=CC(=[N+](C=C3)[O-])CO)=O)C2)O1)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 770776   

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770776(4-((R)-1-((S)-1-((2,2-difluoro-[1,3]dioxolo[4',5':...)
Affinity DataIC50: 18nMAssay Description:FlpIn TRex-MRGPRX2-HEK293 cells (herein TRex-MRPGRX2-HEK) stably transfected to express human MRGPRX2 were maintained at 37oC with 5% CO2 and grown i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770776(4-((R)-1-((S)-1-((2,2-difluoro-[1,3]dioxolo[4',5':...)
Affinity DataIC50: 35nMAssay Description:LAD-2 cells were maintained at 37oC with 5% CO2 and grown in complete StemPro-34 media supplemented with 1% L-Glutamate, 1% penicillin/streptomycin, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535

TargetMas-related G-protein coupled receptor member X2(Human)
Deep Apple Therapeutics

WIPO
LigandPNGBDBM770776(4-((R)-1-((S)-1-((2,2-difluoro-[1,3]dioxolo[4',5':...)
Affinity DataIC50: 128nMAssay Description:LAD-2 cells were maintained at 37oC with 5% CO2 and grown in complete StemPro-34 media supplemented with 1% L-Glutamate, 1% penicillin/streptomycin, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025064535