BDBM770978 N-[2-chloro-4-(trifluoromethyl)phenyl](6-ethyl-5-{4-[(5-hydroxy-6-methyl-4-pyrimidinyl)carbonyl]-1-piperazinyl}-1''-methyl-4-oxo-7H,1''H-1,1'',3,3a,7,7''-hexaaza-2,5''-biindenyl-7-yl)acetamide::WO2025049746, Example 252

SMILES CCc1c(N2CCN(C(=O)c3ncnc(C)c3O)CC2)c(=O)n2nc(-c3cnc4c(ccn4C)c3)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770978   

LigandPNGBDBM770978(N-[2-chloro-4-(trifluoromethyl)phenyl](6-ethyl-5-{...)
Affinity DataIC50: 19nMAssay Description:ATPase activity was measured using the ADP-Glo Kinase Assay following the manufacturers recommended protocol. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025049746

LigandPNGBDBM770978(N-[2-chloro-4-(trifluoromethyl)phenyl](6-ethyl-5-{...)
Affinity DataIC50: 21nMAssay Description:WRN helicase core (8xHis-tev-WRN (480-1251)) was expressed in Sf9 insect cells and purified using HiTrap TALON affinity purification followed by hepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025049746