BDBM770992 N-[2-chloro-4-(trifluoromethyl)phenyl][2-(2,1-benzisothiazol-5-yl)-6-ethyl-5-{4-[(5-hydroxy-6-methyl-4-pyrimidinyl)carbonyl]-1-piperazinyl}-4-oxo-1,3,3a,7-tetraaza-7-indenyl]acetamide::WO2025049746, Example 266

SMILES CCc1c(N2CCN(C(=O)c3ncnc(C)c3O)CC2)c(=O)n2nc(-c3ccc4nscc4c3)nc2n1CC(=O)Nc1ccc(C(F)(F)F)cc1Cl

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 770992   

LigandPNGBDBM770992(N-[2-chloro-4-(trifluoromethyl)phenyl][2-(2,1-benz...)
Affinity DataIC50: 22nMAssay Description:ATPase activity was measured using the ADP-Glo Kinase Assay following the manufacturers recommended protocol. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025049746

LigandPNGBDBM770992(N-[2-chloro-4-(trifluoromethyl)phenyl][2-(2,1-benz...)
Affinity DataIC50: 22nMAssay Description:WRN helicase core (8xHis-tev-WRN (480-1251)) was expressed in Sf9 insect cells and purified using HiTrap TALON affinity purification followed by hepa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/25/2025
Entry Details
WIPO WO2025049746