BDBM771212 US12414952, Example 1.17

SMILES Cc4c(c1ncco1)nc(N)n5nc(CCN2CCc3c(C2)nnn3CC(F)(F)F)nc45

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 771212   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM771212(US12414952, Example 1.17)
Affinity DataIC50: 1.30nMAssay Description:Method (A): Measurement of A2a Binding Affinity Using Radioligand Binding148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL co...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/28/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM771212(US12414952, Example 1.17)
Affinity DataIC50: 35.2nMAssay Description:The reported affinity of the compounds of the invention for the human A2b adenosine receptor was determined experimentally using a radioligand filtra...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/28/2025
Entry Details
US Patent