BDBM7713 4-[N -(5-Methylsulfonyl-2-oxo-1,2-dihydro-indol-3-ylidene)-hydrazino]benzenesulfonamide::4-{2-[(3Z)-5-methanesulfonyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzene-1-sulfonamide::Oxindole-Based Inhibitor 49

SMILES CS(=O)(=O)c1ccc2NC(=O)C(=NNc3ccc(cc3)S(N)(=O)=O)c2c1

InChI Key InChIKey=BXBHQBATRBBMNC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 7713   

TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7713(4-{2-[(3Z)-5-methanesulfonyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 16nMAssay Description:Evaluated for inhibition of human cyclin dependent kinase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Glaxosmithkline

LigandPNGBDBM7713(4-{2-[(3Z)-5-methanesulfonyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 16nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM7713(4-{2-[(3Z)-5-methanesulfonyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
LigandPNGBDBM7713(4-{2-[(3Z)-5-methanesulfonyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 350nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence 1.4 uM ATP/[gamma-32P] ATP. A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Zurich

Curated by ChEMBL
LigandPNGBDBM7713(4-{2-[(3Z)-5-methanesulfonyl-2-oxo-2,3-dihydro-1H-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed