BDBM771368 2,2''-(Ethane-1,2-diylbis(5- carbamoyl-4-methoxy-1H- benzo[d]imidazole-1,2- diyl))bis(3-chlorobenzoic acid) Mixture of three atropisomers (meso and racemate)::US12415785, Example 22

SMILES COc1c(C(N)=O)ccc2c1nc(-c1c(Cl)cccc1C(=O)O)n2CCn1c(-c2c(Cl)cccc2C(=O)O)nc2c(OC)c(C(N)=O)ccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 771368   

LigandPNGBDBM771368(2,2'-(Ethane-1,2-diylbis(5- carbamoyl-4-methoxy-1H...)
Affinity DataKd:  2nMAssay Description:Briefly, approximately 20 nmol of recombinant STING protein in 1×TBS buffer (25 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM DTT) was mixed with of EZ-Link...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetStimulator of interferon genes protein(Human)
Ctxt

US Patent
LigandPNGBDBM771368(2,2'-(Ethane-1,2-diylbis(5- carbamoyl-4-methoxy-1H...)
Affinity DataKd:  77nMAssay Description:Briefly, approximately 20 nmol of recombinant STING protein in 1×TBS buffer (25 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM DTT) was mixed with of EZ-Link...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent