BDBM771397 6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)-N-hydroxynicotinamide ::US12415797, Compound 4

SMILES Cc1nc2c(F)cc(-c3nc(Nc4ccc(C(=O)NO)cn4)ncc3F)cc2n1C(C)C

InChI Key InChIKey=IXLNTZGFRNXEDC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 771397   

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 771397BDBM771397(6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-b...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 771397BDBM771397(6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-b...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 771397BDBM771397(6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-b...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 771397BDBM771397(6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-b...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 771397BDBM771397(6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-b...)
Affinity DataIC50: 300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent