BDBM771400 (E)-3-(4-(((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)(methyl)amino)methyl)phenyl)-N-hydroxyacrylamide ::US12415797, Compound 7

SMILES Cc1nc2c(F)cc(-c3nc(Nc4ccc(N(C)Cc5ccc(/C=C/C(=O)NO)cc5)cn4)ncc3F)cc2n1C(C)C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 771400   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771400((E)-3-(4-(((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2...)
Affinity DataIC50: 30nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771400((E)-3-(4-(((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2...)
Affinity DataIC50: 55nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771400((E)-3-(4-(((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2...)
Affinity DataIC50: 55nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771400((E)-3-(4-(((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2...)
Affinity DataIC50: 300nMAssay Description:In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitors phosphor...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma Co.

US Patent
LigandPNGBDBM771400((E)-3-(4-(((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2...)
Affinity DataIC50: 300nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent