BDBM771596 US12415816, Compound I-22

SMILES CCN1CCN(Cc2cc(NC(=O)N3Cc4ccc(Oc5ccc6nc(NC(=O)C7CC7)sc6n5)cc4C3)cc(C(F)(F)F)c2)CC1

InChI Key InChIKey=MAFRKZTXJWEOAT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771596   

TargetTyrosine-protein kinase JAK2(Human)
Dana-Farber Cancer Institute

US Patent
LigandChemical structure of BindingDB Monomer ID 771596BDBM771596(US12415816, Compound I-22)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/29/2025
Entry Details
US Patent