BDBM771625 US20250092044, Example 3

SMILES CNC(=O)c1c(F)cc(-c2[nH]c3ncc4c(c3c2-c2cccc(F)c2)n([C@@H]2CC[C@@H](NC(=O)OC)C2)c(=O)n4C)cc1F

InChI Key InChIKey=HJHIDWMDTSIDAV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 771625   

LigandChemical structure of BindingDB Monomer ID 771625BDBM771625(US20250092044, Example 3)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Incyte

US Patent
LigandChemical structure of BindingDB Monomer ID 771625BDBM771625(US20250092044, Example 3)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/31/2025
Entry Details
US Patent