BDBM771794 16-chloro-5,22,24-trifluoro-17-hydroxy-8,12-dioxa-19lambda6-thia-20-azatetracyclo[19.3.11,4,18.02,7]hexacosa-1(25),2,4,6,14,16,18(26),21,23-nonaene-13,19,19-trione ::US20250289793, Compound 29

SMILES O=C1OCCCOc2cc(F)ccc2-c2cc(c(F)cc2F)NS(=O)(=O)c2cc1cc(Cl)c2O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771794   

TargetATP-citrate synthase(Human)
Esperion Therapeutics

US Patent
LigandPNGBDBM771794(16-chloro-5,22,24-trifluoro-17-hydroxy-8,12-dioxa-...)
Affinity DataIC50: 60nMAssay Description:Table 2: Compounds of the disclosure were evaluated for their efficacy in inhibiting hACLY using rapid fire mass spectrometry (RF/MS). The final reac...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/2/2026
Entry Details
US Patent