BDBM771803 21,23-difluoro-18,18-dioxo-8,11-dioxa-18λ6-thia-16,19-diazatetracyclo[18.3.1.113,17.02,7]pentacosa-1(23),2(7),3,5,13,17(25),20(24),21-octaene-12,15-dione ::US20250289793, Compound 38

SMILES O=C1OCCOc2ccccc2-c2cc(c(F)cc2F)NS(=O)(=O)c2cc1cc(=O)[nH]2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771803   

TargetATP-citrate synthase(Human)
Esperion Therapeutics

US Patent
LigandPNGBDBM771803(21,23-difluoro-18,18-dioxo-8,11-dioxa-18λ6-thia-16...)
Affinity DataIC50: 60nMAssay Description:Table 2: Compounds of the disclosure were evaluated for their efficacy in inhibiting hACLY using rapid fire mass spectrometry (RF/MS). The final reac...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/2/2026
Entry Details
US Patent