BDBM771808 15-chloro-21,23-difluoro-16-hydroxy-8-methyl-18,18-dioxo-11-oxa-18λ6-thia-19-azatetracyclo[18.3.1.113,17.02,7]pentacosa-1(23),2(7),3,5,13,15,17(25),20(24),21-nonaen-12-one ::US20250289793, Compound 43

SMILES CC1CCOC(=O)c2cc(Cl)c(O)c(c2)S(=O)(=O)Nc2cc(c(F)cc2F)-c2ccccc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771808   

TargetATP-citrate synthase(Human)
Esperion Therapeutics

US Patent
LigandPNGBDBM771808(15-chloro-21,23-difluoro-16-hydroxy-8-methyl-18,18...)
Affinity DataIC50: 60nMAssay Description:Table 2: Compounds of the disclosure were evaluated for their efficacy in inhibiting hACLY using rapid fire mass spectrometry (RF/MS). The final reac...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/2/2026
Entry Details
US Patent