BDBM772287 (R)-6-acetyl-8-cyclopentyl-2-((5-(4-((2-(hydroxymethyl)piperidin-1-yl)sulfonyl)-piperazin-1-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one::US20250289813, Compound A7

SMILES CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCN(S(=O)(=O)N5CCCC[C@@H]5CO)CC4)cn3)nc2n(C2CCCC2)c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 772287   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Onquality Pharmaceuticals China

US Patent
LigandPNGBDBM772287((R)-6-acetyl-8-cyclopentyl-2-((5-(4-((2-(hydroxyme...)
Affinity DataIC50: 200nMAssay Description:A Caliper Mobility Shift assay was used to determine the inhibitory activities of a compound against CDK4/cyclin D1 and CDK6/cyclin D1 in their respe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Human)
Onquality Pharmaceuticals China

US Patent
LigandPNGBDBM772287((R)-6-acetyl-8-cyclopentyl-2-((5-(4-((2-(hydroxyme...)
Affinity DataIC50: 200nMAssay Description:A Caliper Mobility Shift assay was used to determine the inhibitory activities of a compound against CDK4/cyclin D1 and CDK6/cyclin D1 in their respe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent