BDBM772346 5-((1-((7-cyclopropyl-6- oxo-5,6-dihydro-1,5- naphthyridin-3-yl)methyl) pyrrolidin-3-yl)oxy)- N-methylpicolinamide::US20250289814, Compound 14

SMILES CNC(=O)c1ccc(OC2CCN(Cc3cnc4cc(C5CC5)c(=O)[nH]c4c3)C2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 772346   

TargetPoly [ADP-ribose] polymerase 1(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772346(5-((1-((7-cyclopropyl-6- oxo-5,6-dihydro-1,5- naph...)
Affinity DataIC50: 6.60nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772346(5-((1-((7-cyclopropyl-6- oxo-5,6-dihydro-1,5- naph...)
Affinity DataIC50: 1.00E+4nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent