BDBM772354 (R)-5-((1-((7-ethyl-6-oxo- 5,6-dihydro- 1,5-naphthyridin- 3-yl)methyl)pyrrolidin- 3-yl)oxy)-N,6- dimethylpicolinamide::US20250289814, Compound 30

SMILES CCc1cc2ncc(CN3CC[C@@H](Oc4ccc(C(=O)NC)nc4C)C3)cc2[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 772354   

TargetPoly [ADP-ribose] polymerase 1(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772354((R)-5-((1-((7-ethyl-6-oxo- 5,6-dihydro- 1,5-naphth...)
Affinity DataIC50: 4.40nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772354((R)-5-((1-((7-ethyl-6-oxo- 5,6-dihydro- 1,5-naphth...)
Affinity DataIC50: 1.00E+4nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent