BDBM772367 5-((1-(1-(2-ethyl-5-fluoro- 3-oxo-3,4-dihydroquin oxalin-6-yl)ethyl)azetidin- 3-yl)oxy)-6-fluoro-N- methylpicolinamide::US20250289814, Compound 55

SMILES CCc1nc2ccc(C(C)N3CC(Oc4ccc(C(=O)NC)nc4F)C3)c(F)c2[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 772367   

TargetPoly [ADP-ribose] polymerase 1(Human)
Ningbo Newbay Technology Development Co.

US Patent
LigandPNGBDBM772367(5-((1-(1-(2-ethyl-5-fluoro- 3-oxo-3,4-dihydroquin ...)
Affinity DataIC50: 28.1nMAssay Description:FP experiments were carried out at room temperature using no-binding black 384-well microplates. Recombinant full length PARP1 and PARP2 proteins pro...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/4/2026
Entry Details
US Patent